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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYFIP1
All Species:
36.06
Human Site:
T335
Identified Species:
61.03
UniProt:
Q7L576
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L576
NP_001028200.1
1253
145182
T335
N
K
S
R
W
T
C
T
S
S
G
S
S
P
Q
Chimpanzee
Pan troglodytes
XP_001137120
1278
148380
T335
N
K
S
K
W
T
C
T
Q
S
S
I
S
P
Q
Rhesus Macaque
Macaca mulatta
XP_001105005
1359
156392
T416
N
K
S
K
W
T
C
T
Q
S
S
I
S
P
Q
Dog
Lupus familis
XP_536156
1212
140594
T335
N
K
S
R
W
M
C
T
S
S
S
S
S
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q7TMB8
1253
145223
A335
N
K
S
R
W
T
C
A
S
S
S
S
S
P
Q
Rat
Rattus norvegicus
NP_001100987
1253
145239
T335
N
K
S
R
W
T
C
T
S
S
S
S
S
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508077
1255
145699
T335
N
K
S
K
W
T
C
T
Q
S
S
I
S
P
Q
Chicken
Gallus gallus
XP_414567
1253
145683
T335
N
K
S
K
W
T
C
T
Q
S
S
I
S
P
Q
Frog
Xenopus laevis
Q6GQD1
1253
145619
T335
N
K
S
K
W
T
C
T
Q
S
S
I
S
P
Q
Zebra Danio
Brachydanio rerio
Q90YM8
1253
145156
T335
N
K
S
R
W
S
C
T
S
T
G
S
S
P
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VF87
1291
149242
S333
D
S
S
K
W
P
L
S
S
S
N
A
I
S
P
Honey Bee
Apis mellifera
XP_395632
1292
149877
S334
D
A
S
K
W
P
L
S
S
S
S
N
S
I
S
Nematode Worm
Caenorhab. elegans
O44518
1262
144995
L332
Y
E
P
S
K
W
P
L
S
D
K
E
S
D
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q5S2C3
1283
145467
L330
K
F
S
S
Q
T
R
L
L
T
L
P
A
P
H
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.9
81
96
N.A.
99
99.1
N.A.
87.4
87.7
86.9
92.5
N.A.
65.4
67.8
51.7
N.A.
Protein Similarity:
100
92.1
86.9
96.4
N.A.
99.6
99.7
N.A.
93.7
94
93.8
96.9
N.A.
80.4
81.2
70.8
N.A.
P-Site Identity:
100
73.3
73.3
86.6
N.A.
86.6
93.3
N.A.
73.3
73.3
73.3
86.6
N.A.
26.6
33.3
13.3
N.A.
P-Site Similarity:
100
80
80
86.6
N.A.
86.6
93.3
N.A.
80
80
80
100
N.A.
53.3
60
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
8
0
0
0
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
72
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% D
% Glu:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
36
8
8
0
% I
% Lys:
8
72
0
50
8
0
0
0
0
0
8
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
15
15
8
0
8
0
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
72
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% N
% Pro:
0
0
8
0
0
15
8
0
0
0
0
8
0
79
8
% P
% Gln:
0
0
0
0
8
0
0
0
36
0
0
0
0
0
72
% Q
% Arg:
0
0
0
36
0
0
8
0
0
0
0
0
0
0
8
% R
% Ser:
0
8
93
15
0
8
0
15
58
79
65
36
86
8
8
% S
% Thr:
0
0
0
0
0
65
0
65
0
15
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
86
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _